Clinical Research
Hypertension
Low-sodium diets were shown to significantly decrease blood-pressures in patients in a double-blinded study.
Hypertension
Double-blind study of three sodium intakes and long-term effects of sodium restriction in essential hypertension
MacGregor GA, Markandu ND, Sagnella GA, Singer DR, Cappuccio FP. Lancet . 1989;2(8674):1244–7.
For adults between the ages of 20 and 50, the number one source of sodium in their diets is chicken.
Hypertension
Sodium intakes of US children and adults from foods and beverages by location of origin and by specific food source.
Drewnowski A, Rehm CD.Lancet . 1989;2(8674):1244–7. Nutrients . 2013;5(6):1840–55.
A prospective, double-blinded, placebo-controlled randomized trial showed significant blood pressure lowering effect of dietary flaxseed.
Hypertension
Potent antihypertensive action of dietary flaxseed in hypertensive patients.
Rodriguez-Leyva D, Weighell W, Edel AL, et al. Hypertension . 2013;62(6):1081–9.
A randomized control trial showed significant blood pressure lowering amongst those who had an intensive lifestyle interventions versus advice only.
Hypertension
Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure.
Chobanian AV, Bakris GL, Black HR, et al. Hypertension . 2003;42(6):1206–52.
Obesity
Intensive Lifestyle interventions including diet, exercise, and behavioural changes lead to sustained weight loss, as well as improved glucose tolerance, improved physical functioning, and reduced incidence of hypertension.
Obesity
Obesity in older adults: a systematic review of the evidence for diagnosis and treatment.
McTigue KM, Hess R, Ziouras J. Obesity (Silver Spring). 2006 Sep;14(9):1485-97.
The Nurses Health Study showed that those with the highest intake of fruits and vegetables had a 24% decrease in risk for becoming obese.
Obesity
Changes in intake of fruits and vegetables in relation to risk of obesity and weight gain among middle-aged women
He K, Hu FB, Colditz GA et al. Int J ObesRelatMetabDisord. 2004 Dec;28(12):1569-74.
Exercise prevents the loss of muscle tissue and increases visceral fat loss.
Obesity
The effects of exercise training on fat-mass loss in obese patients during energy intake restriction.
Hansen D, Dendale P, Berger J, van Loon LJ, Meeusen R. Sports Med. 2007;37(1):31-46.
Diabetes
The Look AHEAD trial showed the the lifestyle intervention group had significant reduction in A1C, reduction in weight, and improvement in physical fitness.
Diabetes
Obesity in older adults: a systematic review of the evidence for diagnosis and treatment.
McTigue KM, Hess R, Ziouras J. Obesity (Silver Spring). 2006 Sep;14(9):1485-97.
A study of 89 000 Californians showed that vegans decreased their risk of developing Diabetes by 78%.
Diabetes
Vegetarian diets and incidence of diabetes in the Adventist Health Study-2.
Tonstad S, Stewart K, Oda K, Batech M, Herring RP, Fraser GE. NutrMetabCardiovascDis . 2013;23(4):292–9.
A review looking at various diets found patients consuming plant-based meals had improved glycemic control and improved cardiovascular outcomes.
Diabetes
Usefulness of vegetarian and vegan diets for treating type 2 diabetes.
Trapp CB, Barnard ND. CurrDiabRep . 2010;10(2):152–8.
A pilot study of thirteen patients showed that after 7 months on a high-fibre, low-fat plant-based diet, the average A1c dropped from 8.2 to 5.8.
Diabetes
Glycemic and cardiovascular parameters improved in type 2 diabetes with the high nutrient density (HND) diet.
Dunaief DM, Fuhrman J, Dunaief JL, et al. Open J PrevMed . 2012;2(3):364–71.
Coronary Artery Disease
The Lifestyle Heart Trial showed conclusive evidence that intensive lifestyle changes can regress coronary atherosclerosis.
Coronary Artery Disease
Can lifestyle changes reverse coronary heart disease?
Ornish D, et al. The Lifestyle Heart Trial. Lancet 1990 Jul 21;336(8708):129-33.
Coronary Artery Disease
Intensive lifestyle changes for reversal of coronary heart disease.
Ornish D, et al. JAMA 1998 Dec 16;280(23):2001-7.
Non-Alcoholic Fatty Liver Disease
A review of studies showed that intensive Lifestyle interventions including counselling regarding nutrition and exercise helped with weight reduction and an improvement in liver histology.
Non-Alcoholic Fatty Liver Disease
Behavior therapy for nonalcoholic fatty liver disease: The need for a multidisciplinary approach.
302. Bellentani S, Dalle Grave R, Suppini A, Marchesini G; Fatty Liver Italian Network. Hepatology. 2008 Feb;47(2):746-54
Ulcerative Colitis
Treating the ulcerative colitis patient with a plant-based diet has no contraindications or adverse reactions, is affordable and can prevent and treat common comorbidities such as type 2 diabetes and coronary artery disease.
Ulcerative Colitis
Ulcerative Colitis – Prevention and Treatment with a Plant-Based Diet
Rose SD, Strombom AJ; Adv Res Gastroentero Hepatol. 2020 June;15(2):101-106.